The dupondius was introduced during the Roman Republic as a large bronze cast coin, although even at introduction it weighed less than 2 pounds. The initial coins featured the bust of Roma on the obverse and a six-spoked wheel on the reverse.
With the coinage reform of Augustus in about 23 BC, the sestertius and dupondius were produced in a golden colored copper-alloy called orichalcum (brass).
The dupondius was normally further distinguished from the similarly sized as with the addition of a radiate crown to the bust of the emperor in 66 AD during the reign of Nero.

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Reverse: TI CLAVDIVS CAESAR AVG P M TR P IMP S-C, Claudius, togate, standing left, holding simpulum
Die Orientation: 0 H
Weight: 12.6 g
Reverse very worn, but a nice portrait for the grade

Reverse: distyle shrine with arched roof containing statue of the Genius of the Senate, togate, raising hand, holding eagle-tipped scepter, standing on pedestal; COS__IIII / S C
Die Orientation: -
Weight: 13.04 g

Reverse: VOTA SOL DECENN II, Antoninus Pius, standing facing left, sacrificing with patera over tripod, left arm at side; by altar, bull reclining; S-C in fields; COS IIII in exergue
Die Orientation: 12 H
Weight: 13.71 g

Reverse: COS IIII, Antoninus Pius standing facing left, wearing toga, sacrificing with patera over tripod; SC in fields; VOTA in exergue
Die Orientation: 5 H
Weight: 10.85 g

Reverse: TR POT XIX COS IIII, Annona, draped, seated right, holding cornucopiae in both hands: modius with grain stalks at her feet; SC in exergue
Die Orientation: 10 H
Weight: 10.87 g

Reverse: TR POT XIX COS IIII, Providentia, standing left, pointing with right hand at large globe and holding scepter; SC in fields
Die Orientation: 6 H
Weight: 13.45 g

Reverse: TEMPL DIVI AVG REST, Octastyle temple, in which are seated figures of Divus Augustus and Livia; COS IIII in exergue; SC in fields
Die Orientation: 12 H
Weight: 9.6 g
Inscription truncated on this example, and clearly a bust with drapery
Reverse of 1017 is: TEMPLVM DIV AVG REST
Inscription truncated on this example
Ex. Münzen & Medaillen GmbH, Auction 44, Lot 306, November 25th, 2016, Mention of Smoothed Fields (I agree)
Description goes on to say: The temple of Divus Augustus and Livia, started under Tiberius and
consecrated by Caligula, stood on the Capitol in Rome. It was probably renovated under Antoninus
Pius.
Ex. Auktionshaus H. D. Rauch GmbH, E-Auction 19, Lot 256, February 26th, 2016

Reverse: INDVLGENTIA AVG COS IIII, Indulgentia, draped, seated left, extending right hand and holding transverse scepter in left; S-C in exergue
Die Orientation: 6 H
Weight: 9.54 g
"Indulgentia is an allegorical goddess or personification of indulgence, clemency, pardon."
It seems possible that this coin refers to Pius's suspension of the collection of taxes and the offering of grants for rebuilding, namely cities in the province of Asia struck by a major earthquake, specifically perhaps Cyzicus, Ephesus, and Smyrna in 152 AD.
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Reverse: TR POT XIX COS IIII, Annona seated right, holding cornucopia, modius at her feet; SC in exergue
Die Orientation: 12 H
Weight: 11.56 g

Reverse: TR POT XIX COS IIII S C: Fides Exercitus, standing left, holding two standards
Die Orientation: 6 H
Weight: 9.18 g
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Reverse: S·C inside laurel wreath of eight leaves
Die Orientation: 12 H
Weight: 14.77 g
I'm not sure what to make of the ^ under the bust, I see it on others sold of this #, but not all dies, signed die? workshop letter?
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Reverse: SC inside an oak wreath
Die Orientation: 11 H
Weight: 15.54 g
SC stands for "senatus consultum", a decree of the senate.
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Reverse: CN PISO CN F IIIVIR AAAFF, Inscription around large SC
Die Orientation: 4 H
Weight: 11.07 g
RIC dates to 15 BC and 14 BC comes from:
The_moneyer_issues_under_Augustus.pdf by C.G.J. Pannekeet
The obverse inscription translates to "Augustus, Holding power of the Tribune of the Plebs"
The reverse inscription translates to "Gnaeus Piso, son of Gnaeus, One of three magistrates responsible for the casting and striking of gold, silver, and bronze coinage.
SC stands for "senatus consultum", a decree of the senate.

Reverse: C . ASINIVS IIIVIR A A A F F around S C
Die Orientation: 1 H
Weight: 11.66 g
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Reverse: LIBERALITATIS IVL EBOR; Patera, aspergillum, jug, simpulum, and knife
Die Orientation: 6 H
Weight: 21.66 g

Reverse: Chained crocodile standing right; palm and filleted wreath behind COL_NEM
Die Orientation: -
Weight: 13.1 g
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Reverse: Saeculum Frugiferum standing left, holding caduceus with grain ears and trident; SAECVLO FRVGIFERO COS II / S__C
Die Orientation: -
Weight: 10.8 g

Reverse: LIBERTAS AVG IMP II COS P P S C: Libertas, standing left, holding pileus in right hand and rod in left hand
Die Orientation: 6 H
Weight: 7.14 g
Reverse: Juno standing left holding scepter and patera; IVNO LV_CINA / S__C
Die Orientation: -
Weight: 12.92 g

Reverse: CONSECRATIO S C: Vesta, veiled, draped, standing left, sacrificing out of patera in right hand over altar left and holding long lighted torch, vertical, in left
Die Orientation: 5 H
Weight: 13.42 g
RIC says 141 AD, some auction houses say 146, or 147, some say 146-161 AD, during the reign of Pius is all that's certain.

Reverse: Pudicitia seated left, pulling veil and holding scepter; PVDIC_ITIA / S C
Die Orientation: -
Weight: 13.6 g
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Reverse: SIGNIS RECEPT DEVICTIS GERM S C, Germanicus bare-headed and cuirassed, right, with tunic standing, left, right hand raised and left holding aquila
Die Orientation: 6 H
Weight: 14.19 g
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Reverse: SIGNIS RECEPT DEVICTIS GERM, Germanicus, bare-headed, wearing cuirass and short tunic, standing left, cloak over arm in which he cradles aquila, and extending hand in gesture of command; S-C across lower fields
Die Orientation: 6 H
Weight: 11.46 g

Reverse: SIGNIS RECEP DEVICTIS GERM S-C / Germanicus standing left, holding eagle-tipped sceptre
Die Orientation: 0 H
Weight: 0 g
Struck under Caligula.

Reverse: Moesia facing, head left, bull standing right, lion standing left; P M S C_OL VIM / ·AN IIII·
Die Orientation: -
Weight: 6.1 g

Reverse: Salus-Fortuna standing left, stepping on globe, holding patera and rudder; SALVS P_VBLICA / S__C
Die Orientation: -
Weight: 13.78 g
Reverse: COS III, Aequitas seated left, holding scales and cornucopiae; S C in exergue
Die Orientation: 5 H
Weight: 10.41 g

Reverse: M OPPIVS CAPITO PRO PR PRAEF CLASS F C - Two quinqueremes sailing right; caps of Dioscuri above, B below.
Die Orientation: 0 H
Weight: 7.76 g

Reverse: [IMP VIII COS III P P] PAX AETERNA AVG, Pax standing l., holding cornucopiae and setting fire to a pile of arms, S - C in fields
Die Orientation: 0 H
Weight: 10.5 g

Reverse: TR POT XX IMP IIII COS III S C, Victory, winged, naked to waist, standing front, head right, holding palm in right hand and with left hand placing on palm-tree a shield inscribed, VIC PAR
Die Orientation: 6 H
Weight: 11.66 g
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Reverse: SALVTI AVG COS III S C, Salus, draped, standing left, feeding out of patera in right hand snake coiled round altar and holding scepter in left hand
Die Orientation: 0 H
Weight: 0 g

Reverse: IMP VI COS III S C, Jupiter, naked to waist, seated left on throne, holding Victory, standing left and offering crown, on extended right hand, and holding long sceptre in left hand
Die Orientation: 0 H
Weight: 0 g

Reverse: SECVRITAS AVGVSTI S-C, II in ex, Securitas seated right, holding veil above her head, altar at feet right.
Die Orientation: -
Weight: 12.2 g
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Reverse: FORTVNA AVGVST, Fortuna standing left, holding rudder and cornucopiae; S-C across fields
Die Orientation: 6 H
Weight: 12.96 g
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Reverse: PONT MAXIM COS III IMP VII TR POT XXI, Upright caduceus between two crossed cornucopias framing two crossed branches
Die Orientation: 12 H
Weight: 14.76 g
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Reverse: SC inside laurel wreath
Die Orientation: 12 H
Weight: 15.49 g
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Reverse: Blundered Inscription, Caduceus between crossed cornucopias
Die Orientation: 12 H
Weight: 9.6 g
In 17 AD when Antiochus III of Commagene died, Tiberius annexed Commagene to the province of Syria. RIC is confident in the attribution to this mint, RPC is hesitant with Antioch being another possibility based on find evidence. RIC dates to 19-21 AD, whereas RPC goes with 19-20 AD.

Reverse: SENATVS POPVLVSQVE ROMANVS, Trajan advancing right with head turned left, between two trophies; SC below
Die Orientation: 12 H
Weight: -
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Reverse: FORTVNAE REDVCI, Fortuna standing left holding rudder and cornucopiae, S-C across fields
Die Orientation: -
Weight: 10 g

Reverse: Felicitas holding caduceus and cornucopiae; FELICITAS__PVBLICA
Die Orientation: -
Weight: 13.76 g

Reverse: Roma left seated on cuirass, holding wreath and parazonium shield and helmet to the right; ROMA / S C
Die Orientation: -
Weight: 13 g