Prusias II married his maternal cousin Apame IV, a sister of Perseus of Macedon and a princess from the Antigonid dynasty, by whom he had a son, Nicomedes II, and a daughter, Apama,who would marry Dyegilos, son of Cotys IV, King of Thrace.
Towards the end of his life, Prusias II had children by a later wife, and wanted to make them his heirs in place of Nicomedes. He sent Nicomedes to Rome to ask its help in reducing the amount of these reparations, and directed the co-ambassador, Menas, to kill Nicomedes if the mission was unsuccessful. Despite the failure of the mission, Nicomedes persuaded Menas to betray Prusias, and Nicomedes declared himself king. Prusias had to renounce the kingship in favour of his son and was himself murdered in 149 BC.
Reverse: Centaur advancing right, playing lyre; monogram below raised foreleg
Die Orientation: 12 H
Weight: 5.73 g
Reverse: Centaur Chieron walking right, wearing cloak, playing lyre BAΣIΛEΩΣ ΠPOYΣIOY (NΦ)
Die Orientation: -