The classical town was planned according to the orthogonal system. The network of streets, the forum surrounded by an Ionic colonnade and many buildings, a two-nave room later turned into a basilica and other public buildings have been uncovered. The rich architectures and sculptures show a similarity with those of the ancient towns in Asia Minor. Nicopolis ad Istrum had issued coins, bearing images of its own public buildings.
In 447, the town was destroyed by Attila's Huns. In the 6th century, it was rebuilt as a powerful fortress enclosing little more than military buildings and churches, following a very common trend for the cities of that century in the Danube area.
Modern location: Nikyup, Bulgaria

Reverse: NEIKOΠOΛEITΩN PROC ICTRON - Tyche standing facing, head left, holding rod and cornucopia
Die Orientation: 12 H
Weight: 4.54 g

Reverse: Homonoia facing, head left, holding patera and cornucopia; VΠ AΓPIΠΠA NIK_OΠOΛITΩN ΠΡOCIC / TΡΩ
Die Orientation: -
Weight: 12.4 g
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Reverse: VΠ ΑΓΡΙΠΠΑ ΝΙΚΟΠΟΛΙΤΩΝ ΠΡΟC ICT, City-gate flanked by two towers and with a taller third tower rising from center (or from behind)
Die Orientation: 12 H
Weight: 13.72 g
Diadumenian as Caesar under his father Macrinus as Augustus
Marcus Claudius Agrippa as legatus consularis

Reverse: NIKOΠOΛITΩN, serpent-entwined staff of Asklepios
Die Orientation: -
Weight: 1.9 g

Reverse: Asklepian snake-encircled staff; NIKOΠO_ΛITΩN
Die Orientation: -
Weight: 4.3 g

Reverse: VΠ CTA ΛONΓINOV NI[KOΠOΛITΩN] ΠPOC IC / Nemesis-Dikaiosyne standing facing, head left, holding scales and sceptre; wheel at feet
Die Orientation: -
Weight: 16.23 g

Reverse: Hermes standing half left, wearing chalmys, holding purse and kerykeion; NIKOΠOΛIT_ΠPOC ICT
Die Orientation: -
Weight: 3.77 g

Reverse: OOVONI TEPTVLLOV NIKOPOLITWN Julia on left standing right and Septimius Severus on right, standing left, facing each other clasping hands, PROC ICTRWN in exergue
Die Orientation: -
Weight: 9.9 g
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Reverse: VΠ CΤΑ ΛΟΝΓΙΝΟΥ ΝΙΚΟΠΟΛΙΤΩΝ ΠΡΟC ΙCΤΡΟΝ, Artemis standing facing right, holding bow and reaching for an arrow from quiver on her back
Die Orientation: 6 H
Weight: 10.5 g

Reverse: Harpokrates standing left, wearing chalmys, lotus-bud on top of head, right hand to his mouth, holding cornucopia; NIKOΠOΛI_TΩN ΠPOCIC
Die Orientation: -
Weight: 3 g

Reverse: ΝΙΚΟΠΟΛΙ ΠΡΟC ΙCΤΡ, Tyche standing facing, head left, holding rudder and cornucopia
Die Orientation: 6 H
Weight: 2.89 g

Reverse: Nike left leaning on short column, holding wreath and palm frond; NIKOΠOΛIT_ΩN__ΠPOC IC
Die Orientation: -
Weight: 2.9 g

Reverse: Herakles Farnese standing half right, lion skin over left hand, leaning on club; VΠ AV ΓAΛΛOV__NIKOΠOΛITΩN ΠPOCI
Die Orientation: -
Weight: 11.6 g