Coins from Mesopotamia and Osroene
Mesopotamia is a historical region in West Asia situated within the Tigris–Euphrates river system.

The Sumerians and Akkadians (including Assyrians and Babylonians) dominated Mesopotamia from the beginning of written history (c. 3100 BC) to the fall of Babylon in 539 BC, when it was conquered by the Achaemenid Empire. It fell to Alexander the Great in 332 BC, and after his death, it became part of the Greek Seleucid Empire.

Osroene was a historical region in Upper Mesopotamia. It enjoyed semi-autonomy to complete independence from the years of 132 BC to AD 216.

Mesopotamia and Osroene

(1) Caracalla 215-217 AD
Obverse: radiate, draped and cuirassed head right from behind; AVT KAI__ANTΩNEINOC CEB
Reverse: eagle facing, head right, wreath in beak, shrine below; ΔHMAPX EΞ VΠATOC TO Δ
Ref: Prieur 877 (3 examples)
(2) Caracalla 215-217 AD
Obverse: laureate head right; AVT·K·M·A·_·ANTΩNEINOC__·C_EB·
Reverse: eagle facing, head right, wreath in beak, bucranium below; ·_ΔHMAPX·EΞ·_VΠA·TO·Δ_·
Ref: Prieur 820
(3) Gordian III 242 - II 244 AD
AE unit Singara
Obverse: radiate bust right, draped shoulder; AYTOK K M ANT ΓOPΔIANOC CEB
Reverse: turreted bust of Tyche right, Centaur Sagittarius above; AVP CEΠ__KOΛ CINΓAPA
Ref: BMC Arabia 1; SNG Copenhagen 254
(4) Gordian III | Abgar X Frahad bar Manu 241-244 AD
Obverse: radiate, draped and cuirassed bust of Gordian III right from behind; star right AVTOK K M ANT ΓOPΔIANOC CEB
Reverse: bearded draped bust of Abgar X Frahad bar Manu right wearing diademed tiara; star left; ABΓAPOC BACIΛEVC
Ref: SNG Cop 227
(5) Gordian III | Tranquillina 242 - II 244 AD
AE unit Singara
Obverse: Laureate, draped and cuirassed bust of Gordian III right from behind, confronting draped bust of Tranquillina left wearing stephane; AVTOK K M ANT ΓOPΔIANON CAB TPANKVΛΛINA CEB
Reverse: City goddess left seated on rocks, holding branch; Centaur Sagittarius above; river-god swimming below; AVP CEΠ KOΛ CINΓAPA
Ref: BMC Arabia 8, SGICV 3804
(6) Hatra 117-138 AD
AE unit Hatra
Obverse: Radiate bust of Shamash right; HTR DSMS (= Hatra of Shamash)
Reverse: Eagle above S.C upside down
Ref: SNGCop 232
(7) Macrinus 217-218 AD
Obverse: laureate, draped and cuirassed bust right
Reverse: eagle facing, head right, wreath in beak, shrine below; ΔHMAP·X·EΞ VΠATOC
Ref: Prieur 860 (same obverse die)
(8) Philip II Junior 249 AD
AE unit Nisibis
Obverse: radiate and cuirassed bust left; AYTOK K M IOYΛI ΦIΛIΠΠOC CEB
Reverse: facing seated statue of Tyche, ram to the right with head left above and river-god swimming to the right below, all inside tetrastyle temple temple with arched central bay; IOV CEΠ KOΛΩ NECIBI MHT
Ref: BMC 22 corr. (Philip I); SNG Copenh...